Welcome to the Miller Lab at the Medical College of Wisconsin Cancer Center. Our lab is focused on understanding the causes of drug resistance in breast cancer and the discovery of new treatment strategies.
Extensive epigenomic dysregulation is a hallmark of homologous recombination deficiency in triple-negative breast cancer.
Youdinghuan Chen, Lucas A Salas, Jonathan D Marotti, Nicole P Jenkins, Chao Cheng, Todd W Miller, Arminja N Kettenbach, Brock C Christensen.
Int J Cancer. 2024 Dec 5. doi: 10.1002/ijc.35274. Online ahead of print.
Pharmacological induction of chromatin remodeling drives chemosensitization in triple-negative breast cancer.
Meisam Bagheri, Gadisti Aisha Mohamed, Mohammed Ashick Mohamed Saleem, Nevena B Ognjenovic, Hanxu Lu, Fred W Kolling, Owen M Wilkins, Subhadeep Das, Ian S LaCroix, Shivashankar H Nagaraj, Kristen E Muller, Scott A Gerber, Todd W Miller, Diwakar R Pattabiraman.
Cell Rep Med. 2024 Apr 16;5(4):101504. doi: 10.1016/j.xcrm.2024.101504. Epub 2024 Apr 8.
TRIM33 Is a Co-Regulator of Estrogen Receptor Alpha.
Bianca A Romo, Barbara Karakyriakou, Lauren Cressey, Brooke L Brauer, Huijuan Yang, Alexa Warren, Anneka L Johnson, Arminja N Kettenbach, Todd W Miller.
Cancers (Basel). 2024 Feb 20;16(5):845. doi: 10.3390/cancers16050845.