Research in the Miller Laboratory focuses on the identification of cancer signaling pathways and the development of targeted therapies for breast cancer. Our work spans the spectrum of basic cancer biology, through translational studies in mouse models and human tissues, and engages with early-phase clinical trials. We use an array of methods and technologies in these endeavors, including mammalian tissue culture, gene and protein expression and activation profiling, metabolic profiling, chromatin immunoprecipitation, massively parallel DNA sequencing, bioinformatics, mouse models, and live animal imaging.
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