Metformin pharmacology in human cancers: a proof of principle study Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients.
This study determined the concentrations of metformin in blood, plasma, tumor tissue, adipose tissue, and lung tissue in patients with thoracic tumors.
Joseph D Phillips, Darcy B Pooler, Dylan B Ness, Kayla Fay, Steven Tau, Eugene Demidenko, Riley A Hampsch, Lionel D Lewis, Todd W Miller.
Br J Clin Pharmacol. 2023 Mar;89(3):1027-1035. doi: 10.1111/bcp.15546. Epub 2022 Oct 12.
Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients.