Metformin pharmacology in human cancers: a proof of principle study
Metformin pharmacology in human cancers: a proof of principle study Tumour, whole-blood, plasma and tissue concentrations of metformin in lung cancer patients.
NCT03477162
This study determined the concentrations of metformin in blood, plasma, tumor tissue, adipose tissue, and lung tissue in patients with thoracic tumors.
Reference manuscript
Joseph D Phillips, Darcy B Pooler, Dylan B Ness, Kayla Fay, Steven Tau, Eugene Demidenko, Riley A Hampsch, Lionel D Lewis, Todd W Miller.
Br J Clin Pharmacol. 2023 Mar;89(3):1027-1035. doi: 10.1111/bcp.15546. Epub 2022 Oct 12.